SAT Subject Biology Practice Question 452: Answer and Explanation

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Question: 452

2. When during cell division do chromosomes move to opposite poles of the cell?

A. When the centrioles replicate
B. After the nuclear membrane disintegrates
C. Immediately following DNA replication
D. When the DNA condenses
E. Immediately after the centromere splits

Correct Answer: E


E The centromere is the structure that holds the sister chromatids (the replicated DNA) together. As soon as the centromere splits (in anaphase), the sister chromatids (new chromosomes) are pulled to the opposite sides of the cell in preparation for cytokinesis.

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